Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1
Completed · Phase 2
Conditions studied: HIV Infections
In brief
The purpose of this study was to assess the safety, tolerability, antiviral activity, and pharmacokinetics of long-acting cabotegravir (CAB LA) plus the broadly neutralizing monoclonal antibody VRC-HIVMAB075-00-AB (VRC07-523LS), in adults living with HIV-1 with suppressed plasma viremia.
Key facts
- Study ID
- NCT03739996
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 75
- Starts
- 2019-12-31
- Expected to finish
- 2024-04-29
- Last updated by the study team
- 2025-05-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Alabama CRS — Birmingham, Alabama, United States
- UCSD Antiviral Research Center CRS — San Diego, California, United States
- Ucsf Hiv/Aids Crs — San Francisco, California, United States
- University of Colorado Hospital CRS — Aurora, Colorado, United States
- Northwestern University CRS — Chicago, Illinois, United States
- Johns Hopkins University CRS — Baltimore, Maryland, United States
- Washington University Therapeutics (WT) CRS — St Louis, Missouri, United States
- New Jersey Medical School Clinical Research Center CRS — Newark, New Jersey, United States
- Weill Cornell Chelsea CRS — New York, New York, United States
- Columbia P&S CRS — New York, New York, United States
- Weill Cornell Uptown CRS — New York, New York, United States
- University of Rochester Adult HIV Therapeutic Strategies Network CRS — Rochester, New York, United States
- Chapel Hill CRS — Chapel Hill, North Carolina, United States
- Cincinnati Clinical Research Site — Cincinnati, Ohio, United States
- Ohio State University CRS — Columbus, Ohio, United States
- Penn Therapeutics, CRS — Philadelphia, Pennsylvania, United States
- University of Washington AIDS CRS — Seattle, Washington, United States
- Puerto Rico AIDS Clinical Trials Unit CRS — San Juan, Puerto Rico
Full record on ClinicalTrials.gov
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