A Study of LY3090106 in Japanese and Caucasian Healthy Participants

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy

In brief

The main purpose of this study is to evaluate the safety of a study drug known as LY3090106 in healthy Caucasian and Japanese participants. Side effects and tolerability will be documented. Blood samples will be taken to compare how the body handles the drug. The study will last about 12 weeks, not including screening or additional follow-up.

Key facts

Study ID

NCT03736772

Run by

Eli Lilly and Company

People needed

30

Starts

2018-11-19

Expected to finish

2019-03-13

Last updated by the study team

2019-05-03

Who can join

Age: 20 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Overtly healthy Japanese or Caucasian
• Body mass index (BMI) 18.0 - 32.0 kilograms per square meter (kg/m²)

You may not qualify if…

• Have participated, within the last 30 days, in a clinical study involving an investigational product (IP). If the previous IP has a long half-life, 5 half-lives or 30 days (whichever is longer) should have passed
• Have had symptomatic herpes zoster within 3 months of screening
• Show evidence of active or latent tuberculosis (TB)
• Have known hypogammaglobulinemia or a screening serum immunoglobulin (Ig) G <565 milligrams per deciliter (mg/dL)
• Have received live or attenuated vaccine(s) within 1 month of screening, or intend to during the study
• Are immunocompromised
• Have received treatment with biologic agents (such as monoclonal antibodies, including marketed drugs) within 3 months or 5 half-lives (whichever is longer) prior to dosing. Participants with any prior exposure to ixekizumab, tabalumab or other biologic agents directly targeting Interleukin 17 (IL-17) and/or B cells (e.g., rituximab, belimumab, etc.) are excluded

Where it is running

• Anaheim Clinical Trials, LLC — Anaheim, California, United States

Full record on ClinicalTrials.gov

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