Resistance Exercise to Improve Flu Vaccine for Older Adults

Completed · Not applicable

Conditions studied: Influenza, Human

In brief

This study evaluates whether resistance exercise will improve immune responses to the seasonal influenza vaccine in older adults. One third of the participants will perform exercise in the arm that receives the vaccine, one third of the participants will perform the same exercise in the arm that does not receive the vaccine, and one third will only receive the vaccine.

Key facts

Study ID

NCT03736759

Run by

University of Houston

People needed

29

Starts

2018-10-08

Expected to finish

2021-04-01

Last updated by the study team

2022-05-17

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• non-frail older adult (≥65 years old) of any sex and race/ethnicity
• non-smokers (>10 yrs)
• meets American College of Sports Medicine criteria for participation in exercise
• US resident

You may not qualify if…

• underlying medical problems that contraindicate supervised resistance exercise
• past or present history of autoimmune disease, HIV, hepatitis, stroke, or cardiovascular disease
• current debilitating arthritis of the shoulder
• central or peripheral nervous disorders
• bedridden in the past three months
• history of vaccine-related allergies, or severe egg allergy;
• physician-confirmed influenza infection in the prior year
• regular user of corticosteroids
• functional or cognitive impairment that would limit exercise performance or prohibit informed consent
• blood pressure greater than 160/90
• participation in resistance arm exercises in the prior 6 months

Where it is running

• University of Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

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