Cancer Stem Cells in Acute Leukemia

Running, not enrolling

Conditions studied: Acute Leukemia

In brief

Descriptive study of acute leukemia patients. Bone marrow aspirate or peripheral blood samples will be analyzed by next-generation sequencing for novel gene signatures and variations in transcriptional and epigenetic regulatory elements such as ARID5B and SALL4 variants.

Key facts

Study ID

NCT03735797

Run by

Sanford Health

People needed

50

Starts

2017-07-12

Expected to finish

2029-03-01

Last updated by the study team

2026-02-10

Who can join

Age: 0 and older, up to 30. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Newly diagnosed or relapsed acute leukemia (AML or ALL)
• Plan to undergo diagnostic bone marrow aspirate or peripheral blood if clinically indicated (i.e. WBC>50,000 and bone marrow contraindicated)
• Age 1 month to 30 years
• Understand and provide informed consent (subject if>18, legal guardian if<18)

You may not qualify if…

• Age 0 to 4 weeks
• Treatment related leukemia or leukemia secondary to MDS
• Situations that would limit compliance with study requirements or ability to willingly give consent

Where it is running

• Sanford — Fargo, North Dakota, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.