Vitamin D to Improve Outcomes by Leveraging Early Treatment: Long-term Brain Outcomes in Vitamin D Deficient Patients

Completed · Has a placebo group

Conditions studied: Cognitive Decline

In brief

This ancillary study will determine if early administration of a single high-dose (540,000 IU) oral vitamin D3 (cholecalciferol) treatment improves 12-month global cognition and executive function as determined by comprehensive neuropsychological testing in 140 critically ill patients with Vitamin D deficiency at enrollment.

Key facts

Study ID

NCT03733418

Run by

Vanderbilt University Medical Center

People needed

95

Starts

2018-11-01

Expected to finish

2020-02-21

Last updated by the study team

2024-10-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients enrolled in the VIOLET parent study

You may not qualify if…

• Deaf or blind
• Non-English speaking

Where it is running

• University of Colorado Hospital — Aurora, Colorado, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• Montefiore Medical Center — New York, New York, United States
• Oregon Health and Science University Hospital — Portland, Oregon, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States
• Intermountain Medical Center — Murray, Utah, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.