Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

Running, not enrolling · Phase 3

Conditions studied: Muscle Invasive Bladder Cancer

In brief

A Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment and Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder Cancer

Key facts

Study ID

NCT03732677

Run by

AstraZeneca

People needed

1063

Starts

2018-11-16

Expected to finish

2027-11-08

Last updated by the study team

2026-07-17

Who can join

Age: 18 and older, up to 130. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Research Site — Los Angeles, California, United States
• Research Site — Palo Alto, California, United States
• Research Site — New Haven, Connecticut, United States
• Research Site — Chicago, Illinois, United States
• Research Site — Geneva, Illinois, United States
• Research Site — Iowa City, Iowa, United States
• Research Site — Westwood, Kansas, United States
• Research Site — Louisville, Kentucky, United States
• Research Site — New Orleans, Louisiana, United States
• Research Site — Towson, Maryland, United States
• Research Site — Ann Arbor, Michigan, United States
• Research Site — Detroit, Michigan, United States
• Research Site — New York, New York, United States
• Research Site — Rochester, New York, United States
• Research Site — Bethlehem, Pennsylvania, United States
• Research Site — Burlington, Vermont, United States
• Research Site — Milwaukee, Wisconsin, United States
• Research Site — Brisbane, Australia
• Research Site — Elizabeth Vale, Australia
• Research Site — Macquarie University, Australia
• Research Site — Melbourne, Australia
• Research Site — Murdoch, Australia
• Research Site — South Brisbane, Australia
• Research Site — Bruges, Belgium
• Research Site — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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