Laparoscopic Assisted Plane Block (LAPB) Trial

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Opioid Use

In brief

This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks. The investigators will compare bupivacaine (treatment arm 1) versus liposomal bupivacaine (treatment arm 2) versus port site injection of local anesthesia with injection of saline placebo (control). The hypothesis is that liposomal bupivacaine will result in improved analgesia when compared to bupivacaine LAPB and control. The investigators further hypothesize that bupivacaine LAPB will be more effective than the control.

Key facts

Study ID

NCT03730402

Run by

Santa Barbara Cottage Hospital

People needed

34

Starts

2019-02-04

Expected to finish

2021-04-14

Last updated by the study team

2021-07-01

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients aged 18-80 years old
• Patients undergoing non-emergent laparoscopic surgery with planned or continued admission for at least 1 night
• Patients who receive fully laparoscopic procedures including ports up to 15mm, and any blunt dilation of port fascia or sharp extension of skin incisions for specimen extraction.

You may not qualify if…

• Patients under 18 or over 80 years old
• Patients who are pregnant
• Patients who are unable to consent themselves
• Patients who undergo an appendectomy for acute appendicitis
• Patients who undergo emergent surgery
• Patients who are converted to open procedure
• Patients who receive concurrent neuraxial anesthesia (spinal, epidural, or indwelling pain pumps)
• Patients who receive concurrent local anesthetic drips planned during or administered immediately after surgery
• Patients who have a contraindication to local anesthetics (e.g. verified allergy, severe hepatic dysfunction)
• Patients who use chronic narcotics

Where it is running

• Santa Barbara Cottage Hospital — Santa Barbara, California, United States

Full record on ClinicalTrials.gov

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