Midlines and Thrombophlebitis

Completed · Not applicable

Conditions studied: Catheter Infection, Catheter Thrombosis, Catheter Complications

In brief

Peripherally inserted central catheters (PICCs) are central catheters that are placed via peripheral vein under ultrasound guidance and may be used for patients with difficult venous access for long-term central or peripheral infusion therapies as well as central venous pressure monitoring in a critical care setting. Although PICCs provide a great option for some patients, these catheters have known complications including catheter-related bloodstream infection, catheter-related venous thrombosis or clotting, malfunction, and high cost. Midline catheters represent a potentially attractive alternative to PICCs for peripheral infusions. As midlines have increased in popularity and new midlines have been introduced into the market, it is necessary to better understand complication profiles of various midline catheters, as it is likely that all catheters are not created equal. Specifically, the incidence of symptomatic catheter-related thrombosis is of interest. Some midline catheters are coated to provide protection against catheter-related venous thrombosis and/or catheter-related bloodstream infection. The theoretical benefit(s) of these catheters need further validation in human subjects.

Key facts

Study ID

NCT03725293

Run by

Corewell Health East

People needed

212

Starts

2019-01-14

Expected to finish

2020-11-26

Last updated by the study team

2022-01-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All inpatients 18 years of age and older
• Inpatients that require midline catheter placement by the bedside vascular access team

You may not qualify if…

• Do not meet inclusion criteria
• Multiple lumens required
• Alternative diameter of catheter used
• If already enrolled once prior
• Withdraw voluntarily from the study
• Actively (within 24 hours) taking a therapeutic dose of an anticoagulant (heparin, low molecular weight heparin, enoxaparin, rivaroxaban, apixaban, dabigatran, edoxaban, warfarin, arixtra, factor Xa inhibitors)
• Receiving a midline catheter for anticoagulant therapy

Where it is running

• Beaumont Hospital - Royal Oak — Royal Oak, Michigan, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.