Effects of Glutathione on Immunity in Individuals Training for a Marathon

Completed · Not applicable · Has a placebo group

Conditions studied: Healthy

In brief

The aim of this study is to determine the effects of glutathione supplement on the immune cell response and symptomatology of upper respiratory health, and antioxidant capacity in healthy people in exercise-induced model.

Key facts

Study ID

NCT03725241

Run by

University of North Texas, Denton, TX

People needed

84

Starts

2018-10-29

Expected to finish

2020-05-01

Last updated by the study team

2020-11-19

Who can join

Age: 19 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Generally healthy, male or female.
• Between the ages of 19-45 years.
• Have no medical restrictions and no health conditions that would inhibit participant from marathon run.
• Be willing and able to comfortably abstain from any food supplements.
• Not participating as a subject in another study.

You may not qualify if…

• BMI < 20.0 or > 28.5.
• Current or prior use of tobacco products or other inhaled substance.
• More than a moderate intake of alcohol (>1 drink per day in women; >2 drinks per day in men).
• Metabolic or inflammatory disease.
• Excellent fitness based on the American College of Sports Medicine criteria for VO2max based on age and gender.
• Recent weight loss of >10 pounds in the last 3-months.
• Daily intake of ibuprofen, acetaminophen, aspirin, polyphenol supplements, multivitamins, and/or antioxidant supplements.
• Actively attempting (or planning) to lose or gain weight and/or alter body composition.
• Currently taking cholesterol-lowering medications.
• Currently taking prescription anti-inflammatory medications.
• Currently using mouthwash on a regular basis (>4 times per week).
• Orthopedic problems that would limit running capacity.
• Currently in very poor or poor fitness.
• Highly aerobic exercise trained.
• Pregnant or planning to become pregnant during the study period.
• Breast feeding
• Currently taking blood pressure medications.
• Contraindications to strenuous exercise.
• Anemic (blood hemoglobin <10 g/dL and/or hematocrit <35%).
• Diagnosed with asthma or other lung disease.

Where it is running

• University of North Texas — Denton, Texas, United States

Full record on ClinicalTrials.gov

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