Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy
Status unconfirmed
Conditions studied: Cancer
In brief
This is a prospective trial for a computation-based efficacy prediction method for anticancer target therapies. The original computational algorithm utilizes individual transcriptome data of a cancer sample and assesses changes at the level of gene expression and intracellular signaling pathways. By applying the database of known molecular targets of anticancer target drugs it allows to rank potential efficacies of target drugs.
Key facts
- Study ID
- NCT03724097
- Run by
- OmicsWay Corp.
- People needed
- 200
- Starts
- 2017-10-17
- Expected to finish
- 2022-11-01
- Last updated by the study team
- 2021-09-14
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults, diagnosed with cancer;
- Age 18 - 80;
- Patients who previously received anticancer treatment within the standard care, patients for whom standard therapy was not indicated or patients refused to receive standard therapy. Patients could receive an unlimited number of treatment lines before this study;
- Available formalin fixed, paraffin-embedded (FFPE) samples of cancer tissue. The material should be confirmed by a certified pathologist, the sample taken for the analysis should contain at least 70% of tumor cells;
- Anticipated survival of at least 3 months since the patient's inclusion in the current investigation;
- Patients who have signed an informed consent.
You may not qualify if…
- Anticipated survival of less than 3 months since the patient's inclusion in the current investigation;
- Lack of tumor biopsy material, inability to obtain a new tumor biopsy.
Where it is running
- OmicsWay Corp. — Walnut, California, United States
- Kaluga Regional Clinical Oncology Center — Kaluga, Russia
- Oncological Clinical Dispensary No. 1 of the Moscow City Health Department — Moscow, Russia
- Multidisciplinary medical holding "SM-Clinic" — Moscow, Russia
- N.N. Blokhin National Medical Research Center of Oncology — Moscow, Russia
- "Oncobox" Ltd. — Moscow, Russia
- Vitamed LLC — Moscow, Russia
Full record on ClinicalTrials.gov
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