A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Completed · Not applicable

Conditions studied: Knee Osteoarthritis, Post-traumatic Osteoarthritis

In brief

Participants will be enrolled in a prospective clinical trial to assess outcomes in 2 cohorts of patients undergoing unicompartmental versus more extensive biologic OCA transplantation of the knee using MOPSTM-preserved allografts (including menisci), anatomically-shaped allografts, autogenous bone marrow aspirate concentrate (BMC)-treated donor bone, and treatment-specific postoperative rehabilitation.

Key facts

Study ID

NCT03719417

Run by

University of Missouri-Columbia

People needed

14

Starts

2018-12-01

Expected to finish

2022-10-31

Last updated by the study team

2022-11-02

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Grade IV changes in the articular cartilage of the femoral condyle and tibial plateau and meniscal pathology in the medial or lateral femorotibial joint (unicompartmental) or unicompartmental and other femoral condyle, tibial plateau, trochlea and/or patella.
• Between the age of 18-55

You may not qualify if…

• Acute injury to any other part of the affected lower extremity
• Inability to comply with protocol
• BMI greater than 40
• The subject is either pregnant or a prisoner
• Currently involved in worker's compensation case at the time of enrollment

Where it is running

• Missouri Orthopaedic Institute — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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