VIRTUUS Children's Study

Completed

Conditions studied: Renal Transplant Rejection, Pediatric Kidney Disease, End Stage Renal Disease, Nephropathy, BK Virus (Nephropathy), Antibody-mediated Rejection, Acute Cellular Graft Rejection

In brief

The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.

Key facts

Study ID

NCT03719339

Run by

Children's Hospital of Philadelphia

People needed

445

Starts

2017-08-10

Expected to finish

2026-04-30

Last updated by the study team

2026-07-06

Who can join

Age: 2 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males or females between 2 to 18 years at the time of recruitment
• Receiving the first, or additional, incident kidney transplants.
• Have an existing/prevalent transplant with a scheduled kidney allograft biopsy.
• Parental/guardian permission (informed consent) and, if appropriate, child assent.

You may not qualify if…

• Patient's primary medical team feels the subject's participation is not safe.

Where it is running

• University of California-San Diego, Rady Children's Hospital — La Jolla, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• University of California — Los Angeles, California, United States
• Stanford University — Palo Alto, California, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Joan & Sanford I. Weill Medical College of Cornelle University — New York, New York, United States
• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
• CHOP — Philadelphia, Pennsylvania, United States
• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• Seattle Children's Hospital — Seattle, Washington, United States
• Vancouver Children's Hospital — Vancouver, British Columbia, Canada

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.