FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Recruiting now

Conditions studied: FOXP1, Mental Retardation With Language Impairment and With or Without Autistic Features, Autism Spectrum Disorder

In brief

FOXP1, also known as Forkhead-box Protein P1, is a transcription factor protein belonging to the FOX gene family. Disruptions in the FOXP1 gene cause a phenotype characterized by global developmental delay, speech deficits, mild dysmorphic features, and traits of autism spectrum disorder. This study seeks to characterize FOXP1-related neurodevelopmental disorders using a number of genetic, medical and neuropsychological measures.

Key facts

Study ID

NCT03718923

Run by

Icahn School of Medicine at Mount Sinai

People needed

50

Starts

2016-03-28

Expected to finish

2028-05-01

Last updated by the study team

2026-05-28

Who can join

Age: 2 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eligible participants must have a documented variant affecting the FOXP1 gene that the research team determines to be likely or definitely pathogenic.
• Eligible participants must be at least 2 years of age.

You may not qualify if…

• none

Where it is running

• The Seaver Autism Center for Research and Treatment — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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