The Effect of Methylsulfonylmethane (MSM) on Cardiometabolic Health
Completed · Not applicable · Has a placebo group
Conditions studied: Obesity
In brief
Obesity- related diseases are linked to elevated levels of inflammation, oxidative stress, and metabolic dysfunction. Methylsulfonylmethane (MSM) is a naturally occurring compound that demonstrates antioxidant and anti-inflammatory effects. Improvements in measures of metabolic health have been observed in mouse models of obesity and type 2 diabetes following MSM treatment. However, the effect of MSM on obesity-related risk factors for disease in humans has not been investigated. Therefore, the purpose of this investigation will be to determine whether MSM supplementation improves metabolic health, and markers of inflammation and oxidative status.
Key facts
- Study ID
- NCT03716791
- Run by
- Lindsey Miller
- People needed
- 43
- Starts
- 2019-02-19
- Expected to finish
- 2021-08-11
- Last updated by the study team
- 2021-10-05
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- overweight or obese adults without any diagnosed disease or current medications other than birth control. Participants must agree to maintain diet and physical activity levels throughout study.
You may not qualify if…
- normal weight adults, or overweight/obese adults that do not meet the criteria for metabolically unhealthy obesity. Individuals currently on medications, or with diagnosed disease. Pregnant or nursing women, or women planning to become pregnant within the study timeframe. Lack of access to reliable transportation to study site, lack of internet access, or non-english speaking.
Where it is running
- Washington State University — Spokane, Washington, United States
Full record on ClinicalTrials.gov
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