The Safety and Intake Rate of a Natural Compound Arctigenin in Healthy Men
Completed · Not applicable
Conditions studied: Healthy
In brief
The purpose of this research study is to determine if consuming arctigenin, a natural compound from a Chinese herb called Arctium lappa (commonly called greater burdock), is safe, and to measure the intake level of arctigenin in blood. Arctigenin is being studied by researchers for potential health benefits such as helping to lower the risk of inflammation and cancer. A human study has been done measuring the uptake of arctigenin into blood after consumption of the herb extract containing arctigenin, and found no toxicity. Studies in mice demonstrated that consumption of arctigenin in pure form at a safe level is highly effective in inhibition of prostate cancer growth. Therefore, this study is designed to evaluate the safety and uptake rate of pure arctigenin in humans, which may be potentially used in the future for prostate cancer prevention.
Key facts
- Study ID
- NCT03703388
- Run by
- University of California, Los Angeles
- People needed
- 21
- Starts
- 2019-01-15
- Expected to finish
- 2020-07-15
- Last updated by the study team
- 2020-08-04
Who can join
Age: 20 and older, up to 75. Sex: male. Healthy volunteers: accepted.
You may qualify if…
- Subjects consent to participate in the trial;
- The subject is 20-75 years of age;
- The subject is in healthy condition;
- The subject agrees to stop consuming or using arctigenin-containing products and supplement throughout the entire intervention period except for arctigenin capsules provided during study intervention.
You may not qualify if…
- History of hepatitis or liver dysfunction;
- History of kidney disease or dysfunction;
- Ongoing alcohol abuse;
- Significant medical or psychiatric conditions that would make the patient a poor protocol candidate;
- Prior sensitivity or allergic reaction to arctigenin-containing products or supplements;
- Allergies to multiple food items or nutritional supplements;
- Taking antibiotics, anti-diabetic medicines, anti-cancer medicine, LHRH agonists, androgen receptor blocking agents, finasteride, or has undergone bilateral orchiectomy.
Where it is running
- UCLA Center for Human Nutrition, 900 Veteran Avenue, WH 14-187 — Los Angeles, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.