A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population

Completed

Conditions studied: Acute Kidney Injury, Hypotension, Anesthesia; Adverse Effect

In brief

This study proposes to perform a pilot observational study looking at the doses of propofol used for the induction of general anesthesia and its association with the development of hypotension and AKI among elderly patients at YNHH.

Key facts

Study ID

NCT03699696

Run by

Yale University

People needed

541

Starts

2014-12-01

Expected to finish

2018-07-08

Last updated by the study team

2019-01-24

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients age 65 or older who underwent induction of general anesthesia at YNHH
• Only first surgery for each patient within the time period is counted
• Only include patients who underwent intubation
• Only include patients who underwent induction by propofol bolus
• Only include patients who got at least 0.3mg/kg of propofol

You may not qualify if…

• Patients under the age of 65, patients who underwent monitored anesthetic care/conscious mediation for their procedures.
• Patients with renal failure and/or chronic kidney disease
• Patients who have a pre-operative systolic blood pressure <100

Where it is running

• Yale New Haven Health System — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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