Knee Injection RCT

Stopped early · Phase 4

Conditions studied: Osteoarthritis

In brief

Hypothesis: Ketorolac injection is a cost-effective adjunct in the nonoperative treatment of knee osteoarthritis (OA) compared to steroids and viscosupplementation. Aims/objectives: The objective of this randomized, controlled, double-blinded, prospective study is to assess the efficacy and cost-effectiveness of knee injection with ketorolac in the nonsurgical management of symptomatic OA compared to injections with corticosteroids and viscosupplements.

Key facts

Study ID

NCT03694821

Run by

UConn Health

People needed

18

Starts

2018-07-05

Expected to finish

2019-07-16

Last updated by the study team

2020-02-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients over the age of 18 who present with 1) symptomatic knee OA and radiographic evidence of joint space narrowing and 2) are interested in knee injections for pain relief.

You may not qualify if…

• Prior injections into the same knee within the past 6 months,
• Pregnant and/or lactating women,
• Inflammatory joint disease including rheumatoid or psoriatic arthritis,
• Concurrent use of anti-rheumatic drugs,
• Allergy or hypersensitivity to the study medications,
• Patients on an active pain management contract,
• Patients with insurance that requires pre-certification for any of the study drugs,
• Inability to make own decisions regarding the informed consent,
• Inability to read and/or understand English,
• Patients who are unable to return for follow-up or be reached by phone.

Where it is running

• UConn Health — Farmington, Connecticut, United States

Full record on ClinicalTrials.gov

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