Uterine Contractions Under Blue Light

Status unconfirmed · Not applicable

Conditions studied: Preterm Contractions

In brief

The objective in the current study is to test the hypothesis that nocturnal uterine contractions in preterm women can be suppressed by brief ocular exposure to blue light.The Olcese lab at Florida State University identified a novel interaction between the myometrial melatonin receptors and OT receptors in human myometrial cells (Sharkey et al. 2009), which may ultimately help to resolve certain issues surrounding idiopathic preterm labor. Their results consistently indicate that melatonin at physiological concentration sensitizes human myometrial smooth muscle cells to the contractile effects of OT (Sharkey et al. 2010).

Key facts

Study ID

NCT03691740

Run by

University of South Florida

People needed

30

Starts

2018-09-06

Expected to finish

2019-06-01

Last updated by the study team

2018-10-02

Who can join

Age: 18 and older, up to 55. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Pregnant
• Gestational age: 24 to 31 (+6 days) week of pregnancy
• Uterine contractions
• First episode of preterm labor

You may not qualify if…

• Visual impairment (legally blind)
• Multiple pregnancy
• Current progesterone treatment
• Preeclampsia
• Renal disease
• Current chlamydia or gonorrhea infections
• Cocaine or opiate use
• Nightshift work in the past week

Where it is running

• Tampa General Hospital — Tampa, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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