Weight Loss and Cognitive Function in Adults

Completed · Not applicable

Conditions studied: Overweight and Obesity

In brief

More than two-thirds of middle-aged and older adults are overweight, which places them at greater risk of disability and higher medical expenses. Lifestyle interventions which promote weight loss for this population are needed. However, it is not known how different weight loss approaches impact brain (cognitive) functions, such as memory and attention. The investigator's investigation aims to improve adherence to a hypocaloric diet prescription through improved attention and inhibitory control, reduced hunger, and increased satiety. The objectives of this pilot study are to: 1) determine the feasibility and establish proof-of-concept; 2) establish proficiency and feasibility of the proposed cognitive function assessments; and 3) obtain preliminary data for effect size generation.

Key facts

Study ID

NCT03685305

Run by

Virginia Polytechnic Institute and State University

People needed

33

Starts

2018-08-06

Expected to finish

2020-03-31

Last updated by the study team

2025-03-21

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Overweight or obese, BMI 25-40 kg/m\^2
• Able to use a computer, keyboard, and mouse

You may not qualify if…

• Uncontrolled hypertension
• Orthopedic injury
• Other conditions that preclude participation in a walking program
• Previous participation in psychology research which involved computerized cognitive testing
• Diabetes which requires insulin

Where it is running

• Virginia Tech — Blacksburg, Virginia, United States

Full record on ClinicalTrials.gov

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