Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade
Completed · Not applicable · Has a placebo group
Conditions studied: Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left, Phrenic Nerve Palsy on the Right
In brief
One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper extremity surgeries. This type of block can unmask underlying respiratory issues such as shortness of breath due to a well-known and typically insignificant side effect of temporary diaphragmatic paralysis. The nerve block may be able to use saline solution to wash out the local anesthetic and potentially reverse this respiratory side effect. Specifically, the goal of this study is to determine if the injection of saline through the nerve block catheter reverses blockade of the phrenic nerve supplying the diaphragm, without affecting the ability of the nerve block to provide pain control after surgery.
Key facts
- Study ID
- NCT03677778
- Run by
- Stanford University
- People needed
- 43
- Starts
- 2018-10-22
- Expected to finish
- 2022-07-07
- Last updated by the study team
- 2022-08-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All adult patients (18 years and over) scheduled for surgery requiring a continuous interscalene brachial plexus nerve block catheter as part of their anesthetic care.
You may not qualify if…
- Concomitant life-threatening injuries and other concomitant injuries causing significant pain
- Pregnant
- Any condition impairing patient's ability to consent to participation in study, and an existing condition contraindicating a nerve block, i.e. nerve injury, existing bleeding disorder, infection in the vicinity of the block, and patient refusal.
Where it is running
- Stanford Health Care (SHC) — Palo Alto, California, United States
Full record on ClinicalTrials.gov
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