Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

Recruiting now

Conditions studied: Thyroid Gland Nodule

In brief

This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.

Key facts

Study ID

NCT03676647

Run by

City of Hope Medical Center

People needed

22

Starts

2027-01-01

Expected to finish

2028-09-25

Last updated by the study team

2026-06-02

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients undergoing FNA for thyroid nodule diagnosis.
• Any race and ethnicity are eligible for the study.
• Patient should have thyroid nodule(s) with indeterminate diagnosis after FNA (Bethesda category of indeterminate FNA [III-V]).

Where it is running

• City of Hope Medical Center — Duarte, California, United States (enrolling)

Full record on ClinicalTrials.gov

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