Effect of Treatment Modality on Psychosocial Functioning of Survivors of Unilateral Retinoblastoma

Enrolling by invitation

Conditions studied: Survivors of Unilateral Retinoblastoma

In brief

The purpose of this study is to find out about the quality of life and health in patients who had retinoblastoma in one eye (unilateral retinoblastoma), who either received treatment with chemotherapy injected directly into an artery leading to the eye (intra-arterial chemotherapy) or removal of the eye (enucleation). By quality of life, the investigators mean how the participants are feeling about being satisfied with things in their life, including, physical health, emotional health, and their ability to carry out daily activities. The investigators want to see if either treatment option would affect quality of life differently. The investigators hope that this information will help us provide better care to future children with retinoblastoma and better follow-up care for survivors of retinoblastoma.

Key facts

Study ID

NCT03662776

Run by

Memorial Sloan Kettering Cancer Center

People needed

120

Starts

2018-08-31

Expected to finish

2026-08-01

Last updated by the study team

2025-09-03

Who can join

Age: 8 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ability to speak and understand English or Spanish
• Diagnosis of unilateral retinoblastoma at any age, confirmed by the enrolling institution
• Treatment of retinoblastoma between 2006 or later
• Patients must between the age of 8-17 years old
• At least 1 year since completion of all cancer-directed therapy
• Treatment with enucleation of the affected eye or intra-arterial chemotherapy
• Parent of patient:
• Ability to speak and understand English or Spanish
• Ability to confirm that he or she is the parent of a child treated for unilateral retinoblastoma who meets the eligibility criteria listed above
• Ability to provide informed consent

You may not qualify if…

• Patients, or parents of patients, treated with both enucleation and intra-arterial chemotherapy are not eligible

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States
• Texas Children's Hospital (Data Collection) — Houston, Texas, United States

Full record on ClinicalTrials.gov

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