Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
Recruiting now
Conditions studied: Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognition Disorders in Old Age, Cognitive Decline, Cognitive Deterioration
In brief
Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLife https://www.alz.life/) that delivers light therapy at 40 Hz combined with cognitive therapy to improve cognition, function, and quality of life in Alzheimer's disease.
Key facts
- Study ID
- NCT03657745
- Run by
- Alzheimer's Light LLC
- People needed
- 2000
- Starts
- 2018-01-01
- Expected to finish
- 2029-12-31
- Last updated by the study team
- 2024-08-01
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Alzheimer's disease
- Cognitive Impairment
You may not qualify if…
- any previously noted epileptic seizures, including febrile seizures.
- any significant disease of the eye, such as macular degeneration. Since the 40Hz light therapy is delivered via eye stimulation, healthy eyes are required.
Where it is running
- Andrey Vyshedskiy — Miami, Florida, United States (enrolling)
Full record on ClinicalTrials.gov
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