Impact of an Orthotic Intervention in Children With Peripheral Neuropathy

Completed · Not applicable

Conditions studied: Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma, Wilms Tumor

In brief

This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.

Key facts

Study ID

NCT03655587

Run by

Children's Hospitals and Clinics of Minnesota

People needed

27

Starts

2016-09-20

Expected to finish

2022-05-18

Last updated by the study team

2023-02-10

Who can join

Age: 5 and older, up to 14. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 1)between 5-14 years of age; 2)demonstrated neuropathy as evidenced by a Ped-mTNS score>4; 3)normalized step length more than 1 standard deviation below mean for age26 ; 4)ankle DF PROM <10 degrees ; 5) able to give assent according to institutional guidelines; and 6) have parental consent to participate.

You may not qualify if…

• 1)lower extremity sarcomas; 2) central nervous system tumors; 3) an antecedent neurological, developmental, or genetic disorder; and 4)osteonecrosis (ON) 5)Less than antigravity dorsiflexion strength 6) neuroblastoma

Where it is running

• Children's Minnesota — Minneapolis, Minnesota, United States
• St. Jude Children's Research Hospital — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

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