Efficacy Between Serratus Plane Block And Local Infiltration In Vats
Stopped early · Phase 4 · Has a placebo group
Conditions studied: Lung Cancer
In brief
Robotic video-assisted thoracoscopic surgery (VATS) is increasingly being used as it is a less invasive surgery compared to traditional methods, but the acute pain at an early stage after VATS has a major impact on perioperative outcomes. Effective post operative analgesia is believed to reduce morbidity, quicken recovery, improve patient outcome and reduce hospital costs. The site and extent of the incision influences the degree of pain due to disruption of intercostal nerves as well as inflammation of chest wall and pleura. Neuraxial and systemic opioids have been a gold standard as a part of multimodal analgesia for thoracic surgeries. Numerous modalities have been studied: thoracic paravertebral nerve blocks, thoracic epidural analgesia, intercostal nerve blocks, patient controlled analgesia (PCA), cryo-analgesia, transcutaneous electrical nerve stimulation (TENS), inter-pleural blocks, stellate ganglion blocks, long thoracic nerve blocks, and infiltration under direct vision by the surgeon. Serratus plane block is an emerging regional technique that has proven to be effective in comparison to paravertebral blocks in patients undergoing breast surgery and mastectomy with reduced perioperative opioid consumption and improved pain scores. The lateral pectoral nerve, medial pectoral nerve, intercostal nerves and long thoracic nerve are all targets for the serratus plane block. It can be safely performed under ultrasound guidance. The purpose of the study is to evaluate the difference in quality of analgesia between efficacy of serratus plane block and local surgical infiltration by surgeon as measured by patient opioid consumption and pain scores.
Key facts
- Study ID
- NCT03642457
- Run by
- Icahn School of Medicine at Mount Sinai
- People needed
- 65
- Starts
- 2018-03-01
- Expected to finish
- 2018-12-31
- Last updated by the study team
- 2020-09-30
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- ASA (American Society of Anesthesiology) class I-IV
- age 81-75
You may not qualify if…
- ASA class V
- morbid obesity
- patient refusal
- patients with chronic pain or on pain medications
- allergy to LA
- patients receiving any additional regional techniques
- coagulopathy
- patients receiving systemic anticoagulation
- local infection
- procedures anticipated to last more than 5 hours.
Where it is running
- Mount Sinai St. Luke's Hospital — New York, New York, United States
- Mount Sinai West Hospital — New York, New York, United States
Full record on ClinicalTrials.gov
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