Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline

Completed · Phase 2/Phase 3

Conditions studied: Cesarean Section; Infection, Surgical Site Infection

In brief

The purpose of this study is to see whether chlorhexidine is superior to povidine-iodine vaginal antisepsis at reducing bacteria colony counts in pregnant women by comparing three groups: vaginal washing with chlorhexidine-alcohol, vaginal washing with povidine-iodine, and vaginal washing with saline alone.

Key facts

Study ID

NCT03640507

Run by

Columbia University

People needed

30

Starts

2018-10-01

Expected to finish

2019-06-14

Last updated by the study team

2020-06-09

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Pregnant women admitted for cesarean delivery
• Gestational age greater than or equal to 34 weeks

You may not qualify if…

• Rupture of membranes or active labor
• Chorioamnionitis (prior to enrollment)
• Recent (within 4 weeks) antibiotic exposure
• Maternal HIV infection or immunocompromised state
• Known allergy to shellfish, iodine, or chlorhexidine

Where it is running

• New York Presbyterian Hospital at Columbia University and Children's Hospital of New York — New York, New York, United States

Full record on ClinicalTrials.gov

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