Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy
Status unconfirmed · Phase 2
Conditions studied: Lower Urinary Tract Symptoms, Postoperative Urinary Tract Infection
In brief
This study will explore the application of placing heparin into the bladder via a catheter to decrease postoperative lower urinary tract symptoms (LUTS) and urinary tract infection (UTI) symptoms such as urinary frequency, urinary urgency, pain with urination, or difficulty voiding following hysterectomy (surgically removing the uterus). The investigators hypothesize that heparin bladder instillations will reduce LUTS, UTI symptoms, and improve patient satisfaction following hysterectomy.
Key facts
- Study ID
- NCT03633994
- Run by
- The Christ Hospital
- People needed
- 104
- Starts
- 2018-08-20
- Expected to finish
- 2020-03-01
- Last updated by the study team
- 2019-10-10
Who can join
Age: 18 and older, up to 85. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- 18 to 85-years old
- scheduled to undergo a benign hysterectomy
You may not qualify if…
- non-English speakers
- current use of anticoagulants or thrombolytic agents
- known adverse reaction or hypersensitivity to heparin
- history of or active genitourinary tract cancer (bladder, uterine, cervical, ovarian or vaginal)
- history of neurogenic bladder
- pelvic irradiation
- chemical cystitis
- pregnancy
- antibiotic use within the past 30 days
- Surgical procedures involving: anterior or posterior colporrhaphy, vaginal mesh excision, fistula repair, diverticulum repair, urethral reconstruction, planned or incidental cystotomy
Where it is running
- The Christ Hospital — Cincinnati, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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