Treatment of Hypertrophic Scars With Intradermal Botox

Status unconfirmed · Phase 2

Conditions studied: Hypertrophic Scar

In brief

This is a prospective, open label, single center, self-controlled clinical study to demonstrate the safety and efficacy of intradermal botulinum toxin in treating hypertrophic scarring.

Key facts

Study ID

NCT03631368

Run by

Roy G. Geronemus, M.D.

People needed

20

Starts

2018-10-01

Expected to finish

2019-05-31

Last updated by the study team

2018-09-26

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Healthy female and male subjects between the ages 18-75.
• Non-Smoker.
• Fitzpatrick skin type I-VI.
• Desire to improve hypertrophic scarring.
• Able and willing to comply with all visit, treatment and evaluation schedules and requirements.
• Able to understand and provide written Informed Consent.

You may not qualify if…

• Pregnant or planning to become pregnant, having given birth less than 3 months ago, and/or breast feeding.
• Presence of any active systemic or local infections.
• Presence of active local skin disease that may alter wound healing.
• Known allergy to botulinum toxin.
• History of smoking in past 10 years.
• History of chronic drug or alcohol abuse.
• Inability to understand the protocol or to give informed consent.
• History of cosmetic treatments in the area to be treated, including injectable filler of any type within the past year; Botox in the treatment area within the past 6 months; ablative or non-ablative resurfacing/rejuvenation laser treatment or light treatment within the past 6 months, dermabrasion or deep peels within the past 6 months; surgery to the area within the past 6 months.
• History of intralesional corticosteroids or any other injectable medication to the area within the last 3 months.
• History of topical corticosteroids to the area within the past 4 weeks.
• History of any musculoskeletal disease or any weakness in the area to be treated.
• As per the investigator's discretion, any physical or mental condition which might make it unsafe for the subject to participate in this study.

Where it is running

• Laser & Skin Surgery Center of New York — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.