MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation

Completed · Not applicable · Has a placebo group

Conditions studied: Anterior Cruciate Ligament Injury

In brief

This clinical trial evaluates interventions to maximize muscle function and improve cartilage health following anterior cruciate ligament reconstruction. Improving muscle function may improve patient outcomes, improve joint mechanics, and potentially serve as a prevention approach for post-traumatic knee osteoarthritis. Knee osteoarthritis (OA) is a disabling disease that carries a substantial burden to society and to the individual affected.

Key facts

Study ID

NCT03626857

Run by

University of Michigan

People needed

135

Starts

2019-02-22

Expected to finish

2025-01-09

Last updated by the study team

2026-01-02

Who can join

Age: 14 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Acute, complete ACL rupture
• ACL reconstruction with autograft
• Scheduled to undergo ACLR at U of Michigan
• Willingness to participate in testing and follow-up as outlined

You may not qualify if…

• Previous surgery to either knee
• Bony fracture accompanying ACL injury
• Patients who experienced a knee dislocation
• Female participants who are pregnant or planning pregnancy

Where it is running

• MedSport — Ann Arbor, Michigan, United States
• University of Michigan — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.