North American Prodromal Synucleinopathy Consortium

Enrolling by invitation

Conditions studied: REM Sleep Behavior Disorder, Parkinson Disease, Lewy Body Disease, Dementia With Lewy Bodies, Multiple System Atrophy, REM Sleep Parasomnias

In brief

This study will enroll participants with idiopathic rapid eye movement (REM) sleep behavior disorder (RBD), for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.

Key facts

Study ID

NCT03623672

Run by

Washington University School of Medicine

People needed

500

Starts

2018-08-29

Expected to finish

2026-07-31

Last updated by the study team

2024-11-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Idiopathic REM sleep behavior disorder

You may not qualify if…

• REM sleep behavior disorder secondary to another cause (ex: narcolepsy, dementia, Parkinson's Disease, etc)
• Other neurological disorder

Where it is running

• Banner Sun Health Research Institute — Sun City, Arizona, United States
• University of California Los Angeles — Los Angeles, California, United States
• Stanford University — Redwood City, California, United States
• Emory University — Atlanta, Georgia, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Mayo Clinic — Rochester, Minnesota, United States
• Washington University — St Louis, Missouri, United States
• Portland VA Medical Center — Portland, Oregon, United States
• McGill University — Montreal, Quebec, Canada

Full record on ClinicalTrials.gov

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