Improving the Appearance of Skin and Hair in Patients Undergoing Valley Fever Treatment

Stopped early · Not applicable

Conditions studied: Valley Fever, Coccidioidomycosis

In brief

This will be a multi-visit study that will take approximately 3 hours in total. Up to 200 subjects from the BUMC Valley Fever and BUMC Dermatology clinics will be enrolled in this study and assigned to one of three cohorts according to timeline of oral anti-fungal therapy. Subjects in Cohort 1 will be randomized to apply topical cholesterol-containing moisturizers to the skin, hair and lips on either the right or left side of the body daily. Measurements of skin barrier function, appearance of skin and hair, and hair samples will be obtained at baseline and at 4 week follow-up visits. Cohorts 2 and 3 will be observational groups at differing points in oral antifungal treatment regimen. Subjects will be randomized to have measurements of skin barrier function and hair and skin characteristics obtained from either the right or left side of the body at baseline and at monthly follow-up visits.

Key facts

Study ID

NCT03618992

Run by

University of Arizona

People needed

14

Starts

2018-08-01

Expected to finish

2020-05-31

Last updated by the study team

2021-06-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Men and women, age 18 or older
• Patients who have been diagnosed with coccidioidomycosis (valley fever) requiring oral anti-fungal medications such as but not limited to fluconazoles
• Able to comprehend and read the English language

You may not qualify if…

• Subject does not fit inclusion criteria
• Children younger than 18 years of age
• Pregnant women
• Prisoners or those that are cognitively impaired
• Those with known allergies or intolerance to ingredients in the topical formulations
• Subject is unwilling or unable to comply with study procedures
• Unable to read or comprehend English

Where it is running

• University of Arizona - Banner University Medicine Dermatology — Tucson, Arizona, United States
• Valley Fever Center for Excellence — Tucson, Arizona, United States

Full record on ClinicalTrials.gov

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