Neuroimaging Study

Enrolling by invitation · Phase 2

Conditions studied: Cognitive Impairment

In brief

The researchers are trying to gather information and learn more about imaging tests in racially different people who are cognitively normal or have dementia.

Key facts

Study ID

NCT03618186

Run by

Mayo Clinic

People needed

240

Starts

2018-11-26

Expected to finish

2030-05-01

Last updated by the study team

2026-06-12

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female African Americans 30 years of age or older
• Subjects who have completed or are scheduled to undergo the neurological evaluation procedures described below.

You may not qualify if…

• Subjects unable to lie down without moving for 20 minutes.
• Women who are pregnant or cannot stop breast feeding for 24 hours.
• Claustrophobic patients unable to tolerate the scans.
• Subjects with a prolonged QT interval (as demonstrated by ECG test) cannot participate in the Tau-PET scans.
• Standard safety exclusionary criteria for MRI such as metallic foreign bodies, pacemaker, etc, since the quantitative PET data analysis is based on anatomic criteria that are established uniquely for each subject by registration to his/her MRI.

Where it is running

• Mayo Clinic in Florida — Jacksonville, Florida, United States
• Mayo Clinic Minnesota — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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