Immunologic Response to Influenza Vaccination in Children and Adolescents
Completed · Phase 4
Conditions studied: Influenza, Human, Immune Response
In brief
The purpose of this study is to evaluate immunologic response to different types of influenza vaccine among children/adolescents/young adults 4-20 years of age. This is a randomized controlled trial (RCT), that will assess immune response in 120 participants (60 per vaccine arm) pre- and post-vaccination to Flucelvax (egg-free inactivated flu shot) and Fluzone (egg-based inactivated flu shot).
Key facts
- Study ID
- NCT03614975
- Run by
- Richard Zimmerman MD
- People needed
- 166
- Starts
- 2018-09-13
- Expected to finish
- 2018-12-13
- Last updated by the study team
- 2020-01-18
Who can join
Age: 4 and older, up to 20. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- aged 4-20 years;
- has prior vaccination history available (which can be determined based either on medical record review or through state registry review;
- plans to receive the current seasonal influenza vaccination at one of the recruiting sites
You may not qualify if…
- unable or unwilling to completed required study activities, including informed consent, randomization to vaccine, and bloodwork;
- has already received influenza vaccine for the current season;
- has a known immunocompromising condition or is on an immunosuppressing medication (e.g., high dose steroids >10 days);
- is known to be pregnant;
- has a history of severe allergy to eggs or to influenza vaccine or any of its components
Where it is running
- General Academic Pediatrics — Pittsburgh, Pennsylvania, United States
- University of Pittsburgh Department of Family Medicine — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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