Remifentanil Plus Ketamine for Dynamic Flexible Bronchoscopy

Withdrawn before enrolling · Phase 4

Conditions studied: Bronchoscopy

In brief

This randomized controlled pilot clinical trial will enroll patients undergoing dynamic flexible bronchoscopy will be randomized to receive one of the two anesthetic combinations described above. The study will determine if there is a difference when considering patient and physician and satisfaction when performing DFB. Also, safety and efficacy of the two pharmacological combinations (fentanyl + midazolam and remifentanil + ketamine) used will be evaluated.

Key facts

Study ID

NCT03613792

Run by

Beth Israel Deaconess Medical Center

People needed

0

Starts

2023-09-01

Expected to finish

2023-12-01

Last updated by the study team

2023-07-27

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult (>18 years-old)
• Undergoing planned flexible bronchoscopy with dynamic maneuvers for Excessive Central Airway Collapse assessment at Beth Israel Deaconess Medical Center.

You may not qualify if…

• Patients with any past medical history of disease that would put them at risk of receiving one of the four proposed medications. This includes, but it's not limited to, allergies, advanced stage kidney disease, congestive heart failure and non-controlled hypertension.
• With a known/documented history of opioid abuse at any point during life.
• PO2< 60 mmHg or SO2 <85% on room air during any of the encounters with physicians between the moment of initial screening and the procedure itself.
• PaCO2 >60 mmHg
• Planned additional procedure(s) requiring general anesthesia after the dynamic bronchoscopy.

Where it is running

• Beth Israel Deaconess Medical Center (BIDMC) — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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