Fecal Microbiota Transplantation for Irritable Bowel Syndrome

Recruiting now · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Irritable Bowel Syndrome, Fecal Microbiota Transplantation

In brief

Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. FMT has a higher cure rate than standard antibiotic treatment for recurrent Clostridium difficile infections,and shows promising results in Inflammatory bowel disease（IBD）.However, few studies have evaluated whether FMT is effective to treat Irritable bowel syndrome(IBS).The investigators propose to determine the efficiency and safety of FMT in patients with Irritable bowel syndrome.

Key facts

Study ID

NCT03613545

Run by

Guangzhou First People's Hospital

People needed

120

Starts

2018-08-10

Expected to finish

2030-12-31

Last updated by the study team

2021-08-03

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• To be considered eligible for enrolment into the study, subjects must:
• Be able to give written informed consent.
• Males and females aged >18 and <75
• Have IBS as defined by the Rome IV criteria

You may not qualify if…

• Subjects will be excluded from the study if they meet any of the below criteria:
• pregnant or having a follow-up of less than 6 months;
• unable to give informed consent;
• suffering from other severe disease ,including liver and kidney failure, cancers, intestinal diseases, inflammatory bowel disease, C difficile infection;
• unable to undergo endoscopy.

Where it is running

• Guangzhou First People's Hospital — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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