EEG Study of IV Methylphenidate-Induced Emergence From Propofol Sedation

Withdrawn before enrolling · Phase 1/Phase 2

Conditions studied: Anesthesia

In brief

The investigators are performing this research study to find out if intravenous (IV) methylphenidate (commonly known as Ritalin) can help people recover faster from propofol sedation. The investigators also want to know how IV methylphenidate acts in the brain and whether IV methylphenidate is safe to take with an anesthetic (a drug or agent used to decrease or eliminate the feeling of pain by causing unconsciousness) without causing too many side effects. The brain's electrical activity will be studied and recorded using a machine called an electroencephalogram (EEG).

Key facts

Study ID

NCT03610282

Run by

Massachusetts General Hospital

People needed

0

Starts

2019-11-01

Expected to finish

2021-11-01

Last updated by the study team

2020-02-21

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Between the ages of 18 to 45
• Normal body weight and habitus, BMI ≤ 30
• Non-smoker
• No history of taking stimulants
• American Society of Anesthesiologists (ASA) physical status classification P1

You may not qualify if…

• Chronic health conditions

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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