Sex Differences in Reflex Responses to Intermittent Hypoxia

Completed · Not applicable

Conditions studied: Healthy Participants

In brief

The purpose of the present study is to determine whether there are sex differences in the reflex responses to hypoxia in humans.

Key facts

Study ID

NCT03606434

Run by

University of Missouri-Columbia

People needed

40

Starts

2018-09-13

Expected to finish

2021-07-15

Last updated by the study team

2021-07-21

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy adult men and women;
• BMI <30 kg/m2;
• non-pregnant;
• non-breastfeeding;
• non-smokers;
• premenopausal women with a normal menstrual cycle unaffected by hormonal contraceptive use;
• taking no medications known to affect autonomic or cardiovascular function (PI discretion).

You may not qualify if…

• taking any medications known to affect the cardiovascular or autonomic nervous system (e.g. alpha-blockers, beta-blockers, etc);
• a self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological diseases;
• stroke or neurovascular disease;
• bleeding/clotting disorder;
• sleep apnea or other sleep disorders;
• diabetes;
• smoking;
• history of alcoholism or substance abuse;
• hypertension.

Where it is running

• University of Missouri-Columbia — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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