Effect of Music on Reading Comprehension in Patients With Aphasia
Completed · Not applicable
Conditions studied: Aphasia
In brief
The purpose of this investigation is to examine the evidence on emotion, language, and music, and propose a first step, in the form of a single-subject research design, to determine the most effective and efficient method for application to the rehabilitation of patients with aphasia. A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with reading of the lyrics, and priming with music and sung lyrics followed by a reading of the lyrics, with a control condition using reading lyrics without music. Results are expected to provide evidence of independent versus shared processing of music and language at the phrase level applied to the behavior of human subjects with aphasia.
Key facts
- Study ID
- NCT03600987
- Run by
- Carilion Clinic
- People needed
- 4
- Starts
- 2017-10-18
- Expected to finish
- 2019-10-17
- Last updated by the study team
- 2020-01-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Post-hospitalization;
- premorbid reading at the 8th grade level or higher based on the participant's/family's stated years of formal education;
- post-stroke aphasia/left middle cerebral artery (MCA) cerebral vascular accident (CVA) based on electronic medical record (EMR) and computed tomography (CT) and/or magnetic resonance imaging (MRI) imaging reports, or consult with the neurologist;
- intact left amygdala and left extrastriate cortex based on EMR and CT/MRI imaging reports, or consult with the neurologist;
- reliability in answering yes-no questions as determined by an 80% score on therapy tasks during regular speech therapy;
- capacity to provide informed consent concerning a study involving an intervention with music therapy determined by the physician who refers the patient.
You may not qualify if…
- Co-morbidities diagnosed and reported in the EMR or shown on CT scan or MRI including past history of stroke in other brain regions with residual symptoms, dementia, Parkinson disease, head injury, etc.;
- hemianopsia or other visual field defects affecting vision for reading, and in particular right homonymous hemi- or inferior quadrantanopsia;
- previous history of learning disabilities in reading/writing;
- significant psychiatric diagnosis;
- English as a Second Language or non-English language.
Where it is running
- Carilion Franklin Memorial Hospital, Carilion Community Memorial Hospital Inpatient Rehab, Carilion Day Rehab — Rocky Mount, Virginia, United States
Full record on ClinicalTrials.gov
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