Hostile Interpretation Bias Training to Treat Irritability

Completed · Not applicable · Has a placebo group

Conditions studied: Irritable Mood, Mood Disorders

In brief

Hostile interpretation bias may be a feature of severe, chronic irritability in children, one of the most common psychiatric symptoms of childhood. Interpretation bias training (IBT) is a computer-based training program that may reduce irritability in youths. This trial lays the groundwork for a test IBT on irritability.

Key facts

Study ID

NCT03592368

Run by

University of Colorado, Denver

People needed

97

Starts

2018-10-15

Expected to finish

2023-01-27

Last updated by the study team

2024-04-23

Who can join

Age: 13 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adolescents in mental health treatment, with at least:
• mild, clinically significant irritability, and
• typical intellectual functioning (IQ>80)

You may not qualify if…

• Any of the following mental health diagnoses:
• current post-traumatic stress
• lifetime bipolar I or II disorder
• lifetime cyclothymic disorder
• lifetime psychotic disorder
• lifetime autism spectrum disorder
• Major medical problems, including head trauma.
• MRI-specific safety exclusions for the MRI arms.
• Clinical instability.

Where it is running

• University of Colorado, School of Medicine — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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