Arterial Imaging of Inflammation and Resolution After Endovascular Surgery
Completed · Phase 1
Conditions studied: Peripheral Arterial Disease, Claudication, Intermittent, Claudication, PAD, SFA - Superficial Femoral Artery Stenosis, Iliac Artery Disease, Vascular Calcification
In brief
This study evaluates the local inflammatory and resolution response of patients undergoing peripheral vascular intervention like an angioplasty of the superficial femoral artery (SFA) or popliteal artery, or stenting of the iliac artery or SFA, through the use of Positron emission tomography-magnetic resonance imaging (PET/MRI). PET/MRI will be performed prior to intervention, one day and one week after intervention.
Key facts
- Study ID
- NCT03590769
- Run by
- University of California, San Francisco
- People needed
- 9
- Starts
- 2017-06-01
- Expected to finish
- 2019-09-03
- Last updated by the study team
- 2020-11-30
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Over the age of 40,
- With resting or exercise ABI <0.9, TBI <0.6
- Have claudication or limb threatening ischemia \& planning to undergo a percutaneous angioplasty of SFA or popliteal artery, or stenting of the iliac artery or SFA.
You may not qualify if…
- Evidence of active infection
- Hypersensitivity or allergy to contrast agents
- Chronic liver disease, renal disease (GFR< 30) or chronic inflammatory disorders
- Insulin dependent diabetes
- Presence of metal within subject's body, pacemakers, or defibrillators
- BMI < 20 or >35
- Recent other major surgery or illness within 30 days
- Use of immunosuppressive medications or steroids
- History of organ transplantation
- Pregnancy, or plans to become pregnant, or lactating
Where it is running
- San Francisco General Hospital — San Francisco, California, United States
- UCSF — San Francisco, California, United States
Full record on ClinicalTrials.gov
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