The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine

Completed · Not applicable

Conditions studied: Migraine Disorders, Post-Traumatic Headache

In brief

This study evaluates the use of osteopathic manipulation (manual medicine) for migraine headache following traumatic head injury. Headache is an important and very common somatic complaint among people with traumatic brain injury and an important cause of disability in the United States. Over 15-percent of soldiers deployed to Iraq sustained concussion. A majority of these patients suffer from headaches. Many of these are classified as migraine headache that do not respond to medications. Osteopathic manipulation is practiced by physicians in the United States and has been shown to be beneficial in some migraine patients. However, its use in the management of persistent post-traumatic headaches has not been explored. The investigators will use a randomized cross-over design to evaluate post-traumatic migraine patients' response to osteopathic manipulation.

Key facts

Study ID

NCT03588364

Run by

University of California, San Diego

People needed

11

Starts

2016-09-15

Expected to finish

2019-06-01

Last updated by the study team

2019-06-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of TBI, concussion, post-concussive syndrome
• Headache frequency >/equal 4 per month
• Post-traumatic headache, migraine type
• MIDAS Grade I-IV
• Headaches continue to occur 3 months to 1 year after the injury
• No history of uncontrolled migraine prior to head injury

You may not qualify if…

• Headache medication change (Tricyclic antidepressant, antiepileptic medication, propranolol, verapamil, duloxetine, butterbur, Botox) within 30 days
• Non-pharmacologic headache management change (reduction in caffeine intake, reduction in alcohol intake, sleep hygiene, exercise) within 30 days
• Less than 3 months from injury
• History of uncontrolled migraine prior to TBI
• Currently taking oral anti-coagulants

Where it is running

• University of California, San Diego — La Jolla, California, United States

Full record on ClinicalTrials.gov

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