Skeletal Muscle Parameters of Liver Cirrhosis in Non-invasive Imaging and Outcome

Recruiting now

Conditions studied: Liver Cirrhosis

In brief

The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power with TPMT (transverse psoas muscle thickness). Furthermore, the role of myosteatosis, determined in CT by L3-SMI, MRI and ultrasound will be studied.

Key facts

Study ID

NCT03584204

Run by

University Hospital, Bonn

People needed

400

Starts

2018-01-01

Expected to finish

2026-08-31

Last updated by the study team

2021-10-05

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• liver cirrhosis of any etiology
• CT scan available

You may not qualify if…

• HCC or any malignant disease

Where it is running

• University Hospital Bonn — Bonn, Germany (enrolling)
• University of Frankfurt — Frankfurt, Germany (enrolling)
• Sapienza University of Rome — Roma, Italy (enrolling)

Full record on ClinicalTrials.gov

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