Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous

Completed · Not applicable

Conditions studied: Recession, Gingival

In brief

The study will consist of a randomized controlled clinical study trial comparing the results of coronally positioned flap with AlloDerm GBR plus bovine derived xenograft versus coronally positioned tunnel with AlloDerm GBR plus bovine derived xenograft in approximately 30 patients (15 per group). All materials used in the study are FDA approved.

Key facts

Study ID

NCT03582995

Run by

University of Louisville

People needed

12

Starts

2018-10-23

Expected to finish

2021-04-30

Last updated by the study team

2021-06-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• A. At least one Miller Class I or II mucogingival defect ≥ 3 mm (Miller 1985).
• B. The mucogingival defect must be on a non-molar tooth.
• C. Patients must be ≥ 18 years of age.

You may not qualify if…

• A. Patients with debilitating systemic or diseases that significantly affect the periodontium.
• B. Patients with a known allergy to any of the materials that will be used in the study, including systemic antibiotics (tetracycline and doxycycline).
• C. Patients requiring antibiotic prophylaxis.
• D. Root surface restorations at the site of recession.
• E. No detectable CEJ
• F. Patients who fail to maintain oral hygiene levels of at least 80% plaque free surfaces.
• G. Patients who are pregnant or lactating.
• H. Patients who use tobacco products (smoking or smokeless tobacco).
• I. Patients with alcohol abuse problems.
• J. Patients undergoing long-term steroid therapy.
• K. History of previous root coverage procedures, graft or GTR, on the test teeth.
• L. Patients who fail to complete the informed consent form

Where it is running

• Graduate Periodontics, UofL School of Dentistry — Louisville, Kentucky, United States

Full record on ClinicalTrials.gov

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