Prospective Memory Training in Parkinson Disease
Completed · Not applicable
Conditions studied: Parkinson Disease
In brief
The long term goal of this work is to reduce disability among people with Parkinson disease (PD) by enabling them to cope with cognitive decline so they can perform and participate in desired activities and roles. This project focuses on prospective memory, or the ability to remember to execute delayed intentions at the appropriate moment in the future. The current study tests the effects of two primary cognitive intervention approaches (process training \& strategy training) on prospective memory performance in PD. The investigators will conduct a single-blind randomized controlled trial in which individuals with mild cognitive impairment in PD (PD-MCI; N = 90) will complete pre-training assessment, randomization to training group (control, process training, strategy training), four training sessions (process and strategy training groups), and post-training assessment.
Key facts
- Study ID
- NCT03582670
- Run by
- Washington University School of Medicine
- People needed
- 15
- Starts
- 2017-10-01
- Expected to finish
- 2020-07-01
- Last updated by the study team
- 2021-04-06
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Males and females over age 50
- Meet criteria for typical idiopathic PD
- Hoehn \& Yahr stage I-III
- Treated with levodopa/carbidopa
- Have PD with Mild Cognitive Impairment (PD-MCI) according to Movement Disorders Society (MDS) Level II diagnostic criteria.
- Medications should be stable for 4 weeks prior with no changes planned during the study (we will document any unplanned changes).
You may not qualify if…
- Dementia according to MDS criteria or MoCA score <21
- Other neurological disorders,
- Brain surgery
- History of psychotic disorder
- Change in medication during the study
- Treatment with medications that interfere with cognition (e.g. anticholinergics)
- Any condition that would interfere with participation (e.g., non-English speaking, significant current depression).
Where it is running
- Washington University School of Medicine — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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