Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures
Status unconfirmed · Phase 4
Conditions studied: Trauma, Trauma Injury, Pain, Acute
In brief
Management of traumatic rib fractures continues to be a challenge for trauma surgeons. Currently, many analgesic options are available to patients suffering from rib fractures. Formulations currently used for conventional intercostal nerve blocks (CINB) are relatively safe, do not require additional equipment or specialized anesthesia personnel, do not require catheter repositioning, and provide improved analgesia immediately over the aforementioned systemic therapies. A goal of these authors to introduce an additional safe option for extended local analgesia in the setting of multiple rib fractures given the inconclusive evidence supporting or refuting the current standard of care
Key facts
- Study ID
- NCT03574376
- Run by
- Chadrick Evans
- People needed
- 258
- Starts
- 2018-08-29
- Expected to finish
- 2021-08-01
- Last updated by the study team
- 2020-03-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All patients 18 years of age or older suffering 3 or more rib fractures treated by University of Illinois College of Medicine at Peoria (UICOMP) attending or resident physicians at OSF St. Francis Medical Center (OSFMC) are potentially eligible for enrollment in the trial.
You may not qualify if…
- Patients with any of the following will not be eligible since they are contraindications to CEA, LBINB, or both:
- Intracranial hemorrhage
- Fever \>101 degrees Fahrenheit for ≥ 1 hour(s)
- Rash at site of catheter insertion or administration of nerve block
- Hemodynamic instability
- Spinal cord injury
- Vertebral fractures
- Allergy to bupivacaine
- Systemic therapeutic anticoagulation required for duration of hospital admission 20
- Altered mental status without medical decision maker to provide consent
- Patients without the capacity to consent or the lack of a medical decision maker to consent
- Patients that are pregnant
- Legally confined patients.
Where it is running
- Osf St Francis Medical Center — Peoria, Illinois, United States (enrolling)
Full record on ClinicalTrials.gov
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