Effect of Curcumin on Gut Microbiota in IBS
Completed · Not applicable · Has a placebo group
Conditions studied: Irritable Bowel Syndrome
In brief
To evaluate the effect of curcumin food supplement on gut microbiota of children with irritable bowel syndrome (IBS) and to review any correlation between the changes in the microbiota with symptoms.
Key facts
- Study ID
- NCT03568513
- Run by
- Medical College of Wisconsin
- People needed
- 4
- Starts
- 2018-08-01
- Expected to finish
- 2020-01-02
- Last updated by the study team
- 2021-02-21
Who can join
Age: 10 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 10 to 18 years old
- Fulfill the Rome IV criteria for diarrhea predominant IBS
- English speaking
- Able to swallow curcumin/placebo capsules
You may not qualify if…
- Weigh less than 35 kg
- On any form of dietary restrictions
- Taken probiotics one month before enrollment
- Antibiotic treatment one month before enrollment
- IBD
- Celiac disease
- Peptic ulcer disease
- H. Pylori gastritis
- Abnormality of gastrointestinal tract
- Previous abnormal endoscope
- Previous abdominal surgeries
- Gall stones
- Biliary tract obstructions
- Liver pathologies
- Liver failure
- Active GI infection
- Positive stool cultures
- Drug or alcohol abuse
- Concomitant immunological/hematological/neoplastic/heart/ renal/pulmonary condition
- Any other medical condition or taking any form of drug(s) which can explain the current symptoms
- Take oral or intravenous drugs which could have potential drug interaction with curcumin
- Lactating or pregnant or planning to become pregnant
- Developmental delay
- Parents that are developmentally delayed
- Have a diet high in curcumin/turmeric
Where it is running
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.