2-HOBA: Multiple Dosing Study in Healthy Humans
Completed · Not applicable · Has a placebo group
Conditions studied: Healthy Volunteers
In brief
The purpose of this study is to test how well people tolerate a new dietary ingredient called 2-HOBA and how it is metabolized in the body. 2-HOBA is a compound that occurs naturally in buckwheat seeds. This dietary ingredient has been used in animal studies, and single doses have been tolerated well when given to a small group of healthy people. In this study we will test how well people tolerate taking 2-HOBA over 2 weeks and how it is metabolized by the body.
Key facts
- Study ID
- NCT03555682
- Run by
- Metabolic Technologies Inc.
- People needed
- 18
- Starts
- 2018-05-23
- Expected to finish
- 2019-05-10
- Last updated by the study team
- 2019-08-13
Who can join
Age: 18 and older, up to 59. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy individuals between 18 and 59 years old;
- Men and women who are not pregnant at the time of study; and
- Not taking any medication 2 weeks prior to or during the study.
You may not qualify if…
- Inability to give informed consent;
- Diseases that could manifest symptoms or signs that would confound interpretation of the relationship between 2-HOBA action and potential adverse effects;
- Diseases that could manifest morbidity;
- Known cardiac disease, kidney disease, or hepatic dysfunction;
- Need to discontinue any drug that is administered as standard of care treatment; and
- Unwillingness or inability to use approved birth-control methods.
Where it is running
- Vanderbilt University Medical Center — Nashville, Tennessee, United States
Full record on ClinicalTrials.gov
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