Assessment of Biomarkers in Patients With Decompensated Heart Failure and Underlying Coronary Artery Disease
Status unconfirmed
Conditions studied: Heart Failure With Reduced Ejection Fraction, Coronary Artery Disease
In brief
Assessment of Biomarkers in Patients with Decompensated Heart Failure and Underlying Coronary Artery Disease
Key facts
- Study ID
- NCT03551756
- Run by
- CirQuest Labs, LLC
- People needed
- 120
- Starts
- 2018-07-10
- Expected to finish
- 2020-07-01
- Last updated by the study team
- 2020-01-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Group 1: Heart Failure with Coronary Artery Disease Subjects
- Symptomatic heart failure (≥ 3 months) with most recently documented LVEF ≤ 40% (Echo must have been completed in last 12 months prior to enrollment.)
- Significant underlying coronary artery disease as evidenced by:
- previous myocardial infarction
- prior coronary artery bypass graft
- 50% coronary stenosis of one or more arteries and/or
- history of percutaneous coronary intervention with or without stenting
- Age 18 years or older at the first screening visit
- Group 2: Healthy Subjects
- Age 18 years or older at the first screening visit and within 20% of mean age of Group 1 Subjects
You may not qualify if…
- Group 1:
- Documented history of "severe" valvular disease
- Documented history of atrial fibrillation, ventricular fibrillation or ventricular tachycardia.
- Recent or current use of anticoagulant medications such as fXa inhibitors, direct thrombin inhibitors, vitamin K antagonists, or heparin. (within 1 month of screening)
- Group 2:
- Known significant cardiovascular or hematological condition
- Recent or current use of anticoagulant medications such as fXa inhibitors, direct thrombin inhibitors, vitamin K antagonists, or heparin. (within 1 month of screening)
- Recent cold or flu symptoms, respiratory infection or surgery (within 2 weeks of screening)
- History of Asthma
- History of peptic ulcers
Where it is running
- University of Florida — Jacksonville, Florida, United States (enrolling)
- Stern Cardiovascular — Germantown, Tennessee, United States (enrolling)
- CirQuest Labs, LLC — Memphis, Tennessee, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.