Mechanisms of Treatment Change in Panic Disorder and Agoraphobia

Completed · Not applicable

Conditions studied: Panic Disorder With Agoraphobia

In brief

The primary goal of the present study is to identify mechanisms of therapeutic change of two theoretically contrasting therapeutic procedures: The first phase consists of comparing the outcome of the capnometry-assisted breathing therapy (BRT) with cognitive restructuring (CT). During the second phase participants of both interventions will undergo in-vivo exposure.

Key facts

Study ID

NCT03547180

Run by

Southern Methodist University

People needed

41

Starts

2004-01-01

Expected to finish

2008-03-01

Last updated by the study team

2020-05-01

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A current DSM-IV diagnosis of panic disorder with agoraphobia that is designated by the patient as the most important source of current distress
• Patients must be willing to engage in exposure to fearful situations and sensations

You may not qualify if…

• A history of bipolar disorder, psychosis or delusional disorders, current substance abuse or dependence
• Medical Exclusion Factors:
• Patients with severe unstable medical illness, or serious medical illness for which hospitalization may be likely within the next three months
• Patients with a history of seizures, angina, myocardial infarction, congestive heart failure, clinically significant arrhythmias, transient ischemic attacks, cerebrovascular accidents, diabetes mellitus, significant asthma, emphysema, or chronic obstructive pulmonary disease

Where it is running

• Southern Methodist University, Department of Psychology — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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