Genetic Education in BRCA Families
Enrolling by invitation · Not applicable
Conditions studied: BRCA1 Mutation, BRCA2 Mutation
In brief
The primary goal of this research is to test a web-based genetic education intervention that is designed to educate men and women from hereditary cancer families about the personal relevance of genetic testing in order to help them male decisions about whether to pursue genetic testing. We will test this intervention against standard care for men and women from hereditary cancer families. The web-based educational intervention includes all of the information typically covered during genetic counseling. As a result, after completing the education intervention, participants can proceed directly to a brief telephone call with a genetic counselor followed by testing if they choose. A baseline survey will be administered prior to randomization and then follow-up surveys will be administered at 1-month and 6-months post-randomization. Primary outcomes will be completion of genetic counseling, uptake of genetic testing, genetic test results and quality of life.
Key facts
- Study ID
- NCT03544983
- Run by
- Georgetown University
- People needed
- 240
- Starts
- 2020-05-01
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2025-10-29
Who can join
Age: 21 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- A first- (sibling, adult offspring) or second-degree (aunt/uncle, niece/nephew if at-risk parent is deceased) biological relative of an individual with a recently identified BRCA1 or BRCA2 mutation
You may not qualify if…
- Personal diagnosis of metastatic cancer
- Prior genetic testing for hereditary breast/ovarian cancer
- Have one or more children who have tested positive for a BRCA1 or BRCA2 mutation
- Cannot participate in or understand English
- Cannot provide meaningful informed consent
Where it is running
- Georgetown University Medical Center/Lombardi Comprehensive Cancer Center — Washington D.C., District of Columbia, United States
- George Washington University — Washington D.C., District of Columbia, United States
- Dana Farber Cancer Institute — Boston, Massachusetts, United States
- Geisinger Medical Center — Danville, Pennsylvania, United States
Full record on ClinicalTrials.gov
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